EUROAPI
EUROAPI is focused on reinventing active ingredient solutions to sustainably meet customers’ and patients’ needs around the world. We are a leading player in active pharmaceutical ingredients with approximately 200 products in our portfolio, offering a large span of technologies, while developing innovative molecules through our Contract Development and Manufacturing Organization (CDMO) activities.
Taking action for health by enabling access to essential therapies inspires our 3,450 people every day. With strong research and development capabilities and six manufacturing sites all located in Europe (Saint-Aubin-lès-Elbeuf and Vertolaye in France, Brindisi in Italy, Frankfurt in Germany, Budapest in Hungary and Haverhill in the UK), EUROAPI ensures API manufacturing of the highest quality to supply customers in more than 80 countries.
EUROAPI is listed on Euronext Paris.
The EUROAPI Haverhill (UK) site has been established for forty years, located fifteen miles east of Cambridge and sixty miles north of London, within the golden triangle. It employs over 250 people and has built a strong reputation in Flow Chemistry, Active Pharmaceutical Ingredient (API) Spray Drying and as a Contract Development and Manufacturing Organisation (CDMO). Haverhill is proud to house the world’s largest, continuous production, pharmaceutical spray dryer and performs secondary packaging and release activities for oncology and rare disease medicines supporting global markets. The site also offers a contract testing and release facility within its laboratories.
Products and services
Small Molecules Synthesis C(D)MO
APIs, Drug Product Intermediates, Excipients
Spray drying is a primary technology for addressing poor bioavailability. Spray dried dispersions, through stabilising the amorphous form of a drug substance, are a well recognised approach to make poorly soluble compounds clinically effective, often dramatically improving bioavailability compared to the crystalline form.
With 70% to 80% of new drug candidates having low aqueous solubility, enabling technologies are required to enhance bioavailability. Whereas micronization is a good solution for dissolution rate limited solubility, spray drying is best employed when absolute solubility is the issue and the physical form of the API must be altered.
EUROAPI has the widest range of pharma spray drying scales available on the market
- Proof of concept at benchtop lab scale (Buchi) – Output: grams
- GMP ‘Kilo’ Lab scale (Procept SD1) – Output: kilograms
- Clinical and small commercial (GEA PSD2): 10’s kilograms
- Commercial scale (GEA PSD4): 100’s kilograms
- Largest commercial pharma spray dryer in the world (GEA TFD250): 10’s to 100’s metric tons
- All scales supported by advanced mathematical modelling and simulation
Statistical Process Analysis
Our data science team's mission is to use data to drive informed decision-making, solve complex problems, and unlock valuable insights leading to:
Cost reduction and efficiency
Reduction of the number of experimental batches required using a traditional design of experiments approach
Reduction of solvent usage versus a design of experiments approach
Reduction in energy consumption through running less experimental batches during scale up
Simulation of how each new active ingredient will behave at different processing parameters, both in terms of the processability of the product, but also in terms of the quality of the product
Active Pharmaceutical Ingredients Solutions
EUROAPI offers one of the largest API portfolios in the world, numbering nearly 200 ingredients, addressing a wide variety of patients and providing global coverage to more than 80 countries.
Contract Development and Manufacturing CDMO
EUROAPI is the global leader in small molecules APIs, and our innovation and R&D capabilities enable us to accelerate our Contract Development Manufacturing Organization activities in complex molecule segments.
